Discovery of a modified transcription factor endowing yeasts with organic-solvent tolerance and reconstruction of an organic-solvent-tolerant Saccharomyces cerevisiae strain.

نویسندگان

  • Ken Matsui
  • Shinya Teranishi
  • Shohei Kamon
  • Kouichi Kuroda
  • Mitsuyoshi Ueda
چکیده

Organic-solvent tolerance in Saccharomyces cerevisiae strain KK-211, which was first isolated as an organic-solvent-tolerant strain, depends on point mutation (R821S) of the transcription factor Pdr1p. The integration of the PDR1 R821S mutation into wild-type yeast results in organic-solvent tolerance, and the PDR1 R821S mutant can reduce carbonyl compounds in organic solvents.

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عنوان ژورنال:
  • Applied and environmental microbiology

دوره 74 13  شماره 

صفحات  -

تاریخ انتشار 2008